Separation Anxiety: Addressing Variation in Content Uniformity in Compression Processes

Paper Summary

Pharmaceutical scientists are responsible for developing formulas and designing processes that ensure the content uniformity of tablets and capsules.  Unfortunately, a number of scientists who formulate products and who select and/or design processing equipment lack in-depth understanding of powder blending and segregation.  As a result, processes may be developed that are not capable of providing the required content uniformity of the dosage units.  This article focuses on identifying and addressing variation in content uniformity.

Tablets & Capsules, March 2010.